Sickle Cell Disease Ontology Project

Blood Transfusion

http://scdontology.h3abionet.org/ontology/SCDO_0000147


The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)

Term info

dc:source

http://www.hindawi.com/journals/ah/2010/272940/, Radha Raghupathy, Deepa Manwani, and Jane A. Little, “Iron Overload in Sickle Cell Disease,” Advances in Hematology, vol. 2010, Article ID 272940, 9 pages, 2010. doi:10.1155/2010/272940

definition source

http://purl.bioontology.org/ontology/MESH/D001803

Blood Transfusions

rdfs:comment

The major and unavoidable complication of transfusions in sickle cell disease is iron overload. Transfusion is well-defined as prophylaxis (stroke) and as therapy (acute chest syndrome and stroke) for major complications of sickle cell disease and has been instituted, based on less conclusive data, for a range of additional complications, such as priapism, vaso-occlusive crises, leg ulcers, pulmonary hypertension, and during complicated pregnancies.