Proteinuria
Increased amounts of any protein (including albumin) in the urine - typically more than 300mg in a 24hr period.
Sickle Cell Disease Ontology Project
Term info
database cross reference
- DOID:576
- HP:0000093
curator note
Suggest update to description in HPO.
database cross reference
HP:0000093, DOID:576
dc:source
http://www.nhlbi.nih.gov/health-pro/guidelines/sickle-cell-disease-guidelines
definition source
http://purl.obolibrary.org/obo/HP_0000093
existence in other ontologies
Suggest update to description
has age of onset
In sickle cell disease, overt proteinuria (distinguised from albuminuria) may be noted in childhood although less common (4.5% in ages 2-21 [Wigfall 2000] v. 26% in adults [Guasch 2006]).
has disease stage
At most severe form - lead to nephrotic syndrome.
High Urine Protein Levels
is caused by
Caused by a variety of kidney diseases, including sickle cell disease, diabetes, glomerular disease, arteriosclerosis.
Elevated amounts of protein in the urine - typically greater than 300mg in 24 hrs.
rdfs:comment
Screening Recommendations: Screen all individuals with SCD, beginning by age 10, for proteinuria. If the result is negative, repeat screening annually. If the result is positive, perform a first morning void urine albumin-creatinine ratio and if abnormal, consult with or refer to a renal specialist.