Sickle Cell Disease Ontology Project

Glomerulonephritis

http://scdontology.h3abionet.org/ontology/SCDO_0000458


Inflammation of the renal glomeruli.

Term info

curator note

Provide source for additional info.

definition source

http://purl.obolibrary.org/obo/HP_0000099

has age of onset

May occur at any age.

GN, Glomerular Nephritis

is caused by

Variety of causes - in sickle cell disease, most common lesion is focal segmental glomerulosclerosis (FSGS) but also reported Membranoproliferative glomerulonephritis and other forms of glomerulonephritis.

Patients with hematuria may have dark-colored urine. Glomerulonephritis may lead to the proteinuria and "foamy" appearance of the urine. If the latter is substantial, patients may develop clinically evident edema.

Term relations