Severely increased amount of excretion of protein in the urine, defined as 3.5 grams per day or more in adults and 40 mg per meter-squared body surface area per hour in children, or urine protein to creatinine ratio >2000 mg/g [>200 mg/mmol] in children.
Suggest update to description in HPO.
HP:0012593
http://www.kdigo.org/clinical_practice_guidelines/pdf/KDIGO-GN-Guideline.pdf, http://purl.obolibrary.org/obo/HP_0012593
http://www.kdigo.org/clinical_practice_guidelines/pdf/KDIGO-GN-Guideline.pdf, http://purl.obolibrary.org/obo/HP_0012593
Suggest update to description
In sickle cell disease, seen primarily in adult population but may develop in childhood if secondary cause occurs.
Nephrotic-Range Proteinuria
Glomerular diseases that lead to protein loss in the urine (See Nephrotic Syndrome).
Severely increased amount of excretion of protein in the urine, defined as 3.5 grams per day or more in adults and 40 mg per meter-squared body surface area per hour in children, or urine protein to creatinine ratio >2000 mg/g [>200 mg/mmol] in children.
Is diagnosed by assessment of proteinuria (see Proteinuria) by 24hr urine collection or by urine protein-creatinine ratio on spot urine sample [KDIGO 2012].
