Sickle Cell Disease Ontology Project

Sickle Cell Disease-S/C-Harlem

http://scdontology.h3abionet.org/ontology/SCDO_1000062


A rare type of sickle cell disease with the compound heterozygous genotype involving the mutations for Hemoglobin S and Hemoglobin C-Harlem. This condition is described to have a clinical course similar to sickle cell anemia.

Term info

curator note

Request inclusion into relevant ontology

dc:creator

SCDO (Clair Ingram)

definition source

Moo-Penn, W., Bechtel, K., Jue, D., Chan, M.S., Hopkins, G., Schneider, N.J., Wright, J. and Schmidt, R.M., 1975. The presence of hemoglobin S and C Harlem in an individual in the United States. Blood, 46(3), pp.363-367.

Sickle Cell-Hemoglobin C-Harlem Disease, SC(Harlem) Disease