Sickle Cell Disease Ontology Project

Renal Tubular Acidosis

http://scdontology.h3abionet.org/ontology/SCDO_0000986

Acidosis owing to malfunction of the kidney tubules with accumulation of metabolic acids and hyperchloremia.

Term info

database cross reference
  • DOID:14219
  • HP:0001947
curator note

Suggest update to description in HPO. Provide source for additional info.

database cross reference

DOID:14219, HP:0001947

definition source

http://purl.obolibrary.org/obo/HP_0001947

existence in other ontologies

Suggest update to description

has disease stage

Has multiple types - Type 1 (Distal RTA), Type 2 (Proximal RTA), Type 4 (Hyperkalemic RTA). Sickle cell disease may demonstrate a voltage dependent Type 1 RTA.

Accumulation of Acid in Body Due to Kidney Problem, RTA

is caused by

Defects in the kidneys in reabsorption of bicarbonate (HCO3), the excretion of hydrogen ions (H+), or both.

A relatively normal GFR and a metabolic acidosis accompanied by hyperchloremia and a normal plasma anion gap.

Term relations