Sickle Cell Disease Ontology Project

Chronic Kidney Disease

http://scdontology.h3abionet.org/ontology/SCDO_0000226


Chronic kidney disease (CKD) is defined as either having a glomerular filtration rate (GFR) of <60 mL/min/1.73 mL for >3 months with or without kidney damage or having evidence of kidney damage for 3 months, with or without decreased GFR.

Term info

curator note

Suggest update to description in DO (currently no definition).

dc:creator

SCDO

dc:source

http://www.nice.org.uk/guidance/cg182/chapter/1-Recommendations#classification-of-chronic-kidney-disease-2, NHLBI SCD New guidelines 2014.

definition source

NHLBI SCD New guidelines 2014.

existence in other ontologies

Few but definitions not specific enough

has age of onset

When assessed by albuminuria, often presents in second decade of life in sickle cell disease and prevalence increases with age.

has disease stage

CKD is classified using a combination of GFR and ACR categories

Chronic Kidney Injury, Chronic Renal Failure, CKD

is caused by

Sickle cell disease, hypertension, diabetes, polycystic kidney disease, glomerulonephritis, various other causes.

Reduced glomerular filtration, elevated creatinine, anemia, bone disease, uremia.

rdfs:comment

Evidence of kidney damage includes pathologic abnormalities or markers of kidney damage (i.e., proteinuria) independent of cause. Kidney disease severity is classified into five stages according to the level of GFR and presence of albuminuria.