Sickle Cell Disease Ontology Project

Alpha Thalassemia Trait

http://scdontology.h3abionet.org/ontology/SCDO_0000044

A condition in which a person has reduced protein production from two of the four alpha-globin alleles.

Term info

dc:source

https://www.snpedia.com/index.php/Alpha_Thalassemia

definition source

http://bioportal.bioontology.org/ontologies/NCIT/?p=classes&conceptid=http%3A%2F%2Fncicb.nci.nih.gov%2Fxml%2Fowl%2FEVS%2FThesaurus.owl%23C95535

Alpha-Thalassemia Trait

rdfs:comment

-/- alpha/alpha or -/alpha -/alpha. It can exist in two forms: (1) alpha-thal-1 (alpha alpha/--), involves cis deletion of both alpha genes on the same chromosome; (2) alpha-thal-2 (alpha-/alpha-), involves trans deletion of alpha genes this occurs on different (homologous) chromosomes.