Sickle Cell Disease Ontology Project

Acute Tubular Necrosis

http://scdontology.h3abionet.org/ontology/SCDO_0000020

Acute death of renal tubular cells that usually results from prolonged renal ischemia, nephrotoxins, or sepsis.

Term info

curator note

Provide source for additional info.

definition source

http://purl.obolibrary.org/obo/HP_0008682

has age of onset

Can occur at any age.

has disease stage

The clinical course of acute tubular necrosis may be divided into initiation, maintenance, and recovery phases.

Renal Tubular Necrosis, ATN

is caused by

Renal ischemia (which can occur due to prolonged prerenal states), nephrotoxins, or sepsis. In sickle cell disease, may occur due to renal ischemia related to sickle crisis.

Loss of kidney function, reduced urine output, elevated serum creatinine.

Term relations

Subclass of: